Lateral interactions in amblyopia

Spatial interactions in amblyopia: Effects of stimulus parameters and amblyopia type

Adults with amblyopia were recently shown to perform abnormally in tasks requiring integration of local features into global percepts. Moreover, spatial interactions in amblyopic patients, though often found to be abnormal, showed marked variability. Here we measured collinear lateral interactions using Gabor patches in a large number of amblyopic (N=75) and normal subjects (N=25), testing four...

Local and non-local deficits in amblyopia: acuity and spatial interactions

Amblyopic vision is thought to be limited by abnormal long-range spatial interactions, but their exact mode of action and relationship to the main amblyopic deficit in visual acuity is largely unknown. We studied this relationship in a group (N=59) of anisometropic (N=21) and strabismic (or combined, N=38) subjects, using (1) a single and multi-pattern (crowded) computerized static Tumbling-E t...

Spatial and temporal crowding in amblyopia

Spatial crowding is a well-known deficit in amblyopia. We have previously reported evidence suggesting that the inability to isolate stimuli in space in crowded displays (spatial crowding) is a largely independent component of the amblyopic deficit in visual acuity, which is typically found in strabismic amblyopia [Bonneh, Y., Sagi, D., & Polat, U. (2004a). Local and non-local deficits in ambly...

Effective connectivity anomalies in human amblyopia

We investigate the effective connectivity in the lateral geniculate nucleus and visual cortex of humans with amblyopia. Six amblyopes participated in this study. Standard retinotopic mapping stimuli were used to define the boundaries of early visual cortical areas. We obtained fMRI time series from thalamic, striate and extrastriate cortical regions for the connectivity study. Thalamo-striate a...

National Program on Amblyopia Prevention in Islamic Republic of Iran